It’s also worth summarizing some of my analysis timeline in simple bullet-point format, documented in my long series of articles:
Over the decades America has spent $100 billion creating the world’s largest biowarfare capability.
In 2017 Trump brought on board Robert Kadlec, who since the late 1990s had been America’s leading biowarfare advocate.
In 2018 and 2019 mysterious viral epidemics devastated China’s poultry and pork industries, severely damaging China’s food supply.
From January to August 2019, Kadlec ran the Federal/State “Crimson Contagion” exercise in which our government officials practiced their strategies of protecting American society from infection by a hypothetical dangerous respiratory virus that might suddenly appear in China.
In late October 2019, 300 American military servicemen visited Wuhan to participate in the World Military Games.
In late October/early November, Patient Zero in Wuhan became infected with Covid. The virus spread invisibly until the Chinese government discovered its presence near the end of December. The Chinese government finally reacted in early/mid-January.
In early January 2020, America assassinated Iran’s top military leader, with the retaliatory Iranian missile strike nearly leading to war.
In mid/late January 2020, the Wuhan virus suddenly jumped 3,500 miles to the Holy City of Qom, soon infecting Iran’s top political elites, with a number of them dying as a consequence. By February, Iran had become the second global epicenter of the Covid outbreak despite having a negligible Chinese population, while the later outbreaks in Italy and Spain were in locations with hundreds of thousands of Chinese.
In early March 2020, the Iranian government publicly accused America of having launched a biowarfare attack with Covid against Iran and China, with a formal complaint being submitted to the UN. However, virtually no Western media reported those accusations, so almost no Americans became aware of them.
In early April, four intelligence sources told ABC News that a secret November DIA report had described a “potentially cataclysmic” disease outbreak taking place in Wuhan, but this had been ignored by the Trump Administration. Israeli TV confirmed that Israel and NATO allies had received that report, which had been produced “in the second week of November.” But according to best current estimates, at that point only perhaps a dozen people were starting to feel a little sick in Wuhan, a city of 11 million.
“…..we are left with the strong likelihood that Covid came from a laboratory (and) was designed as a bioweapon… China was the intended target (and) America seems the likely source of the attack… The most likely suspects would be rogue elements of our national security establishment… The virus and its dispersal devices might have been obtained from Ft. Detrick and CIA operatives… would have been sent to Wuhan to release it.” Ron Unz, Editor of The Unz Review; from the text
Question 1– What makes your theory about the origins of SARS-CoV-2 so controversial, is not that it suggests that the pathogen was created in a lab, but that it is, in fact, a bioweapon that was deliberately released by US agents prosecuting a secret war on presumed enemies of the United States. Here’s the “money quote” from your article titled, “American Pravda: George Orwell’s Virus Lab-Leak”:
“…..we are left with the strong likelihood that Covid came from a laboratory along with a good possibility that it was designed as a bioweapon, yet we lack serious indications that any lab-leak occurred. So if the original Wuhan outbreak was due to the deployment of a powerful bioweapon but not one that had accidentally leaked from any lab, then surely China was the intended target, the victim rather than the perpetrator….
Given our ongoing military and geopolitical confrontation with China, America seems the likely source of the attack… The most likely suspects would be rogue elements of our national security establishment, probably some of the Deep State Neocons whom Trump had placed near the top of his administration.
This small handful of high-level plotters would have then drawn upon the resources of the American national security apparatus to actually carry out the operation. The virus and its dispersal devices might have been obtained from Ft. Detrick and CIA operatives or members of special forces would have been sent to Wuhan to release it…. In effect, what happened was a Dr. Strangelove-type scenario, but brought to real life.” (“American Pravda: George Orwell’s Virus Lab-Leak”, Ron Unz, The Unz Review)
So, here’s the question: Do you think recent developments lend credibility to your explosive theory or do you now believe that Covid-19 was merely “accidentally” leaked through human error?
Over the past few days, the mainstream press has vigorously pushed back against a theory about the origins of the coronavirus that has now infected as many as 70,000+ people in Wuhan alone (depending on whom you believe). The theory is that China obtained the coronavirus via a Canadian research program, and started molding it into a bioweapon at the Institute of Virology in Wuhan. Politifact pointed the finger at Zero Hedge, in particular, though the story was widely shared across independent-leaning media.
The theory is that the virus, which was developed by infectious disease experts to function as a bio-weapon, originated in the Wuhan-based lab of Dr. Peng Zhou, China's preeminent researcher of bat immune systems, specifically in how their immune systems adapt to the presence of viruses like coronavirus and other destructive viruses. Somehow, the virus escaped from the lab, and the Hunan fish market where the virus supposedly originated is merely a ruse.
Now, a respected epidemiologist who recently caught flack for claiming in a twitter threat that the virus appeared to be much more contagious than initially believed is pointing out irregularities in the virus's genome that suggests it might have been genetically engineered for the purposes of a weapon, and not just any weapon but the deadliest one of all.
For those pressed for time, here are the key findings from the paper, which first focuses on the unique nature of 2019-nCoV, and then observe four amino acid sequences in the Wuhan Coronavirus which are homologous to amino acid sequences in HIV1:
Our phylogentic tree of full-length coronaviruses suggests that 2019-nCoV is closely related to SARS CoV [Fig1].
In addition, other recent studies have linked the 2019-nCoV to SARS CoV. We therefore compared the spike glycoprotein sequences of the 2019-nCoV to that of the SARS CoV (NCBI Accession number: AY390556.1). On careful examination of the sequence alignment we found that the 2019- nCoV spike glycoprotein contains 4 insertions [Fig.2]. To further investigate if these inserts are present in any other corona virus, we performed a multiple sequence alignment of the spike glycoprotein amino acid sequences of all available coronaviruses (n=55) [refer Table S.File1] in NCBI refseq (ncbi.nlm.nih.gov) this includes one sequence of 2019-nCoV[Fig.S1]. We found that these 4 insertions [inserts 1, 2, 3 and 4] are unique to 2019-nCoV and are not present in other coronaviruses analyzed. Another group from China had documented three insertions comparing fewer spike glycoprotein sequences of coronaviruses . Another group from China had documented three insertions comparing fewer spike glycoprotein sequences of coronaviruses (Zhou et al., 2020).
We then translated the aligned genome and found that these inserts are present in all Wuhan 2019-nCoV viruses except the 2019-nCoV virus of Bat as a host [Fig.S4]. Intrigued by the 4 highly conserved inserts unique to 2019-nCoV we wanted to understand their origin. For this purpose, we used the 2019-nCoV local alignment with each insert as query against all virus genomes and considered hits with 100% sequence coverage. Surprisingly, each of the four inserts aligned with short segments of the Human immunodeficiency Virus-1 (HIV-1) proteins. The amino acid positions of the inserts in 2019-nCoV and the corresponding residues in HIV-1 gp120 and HIV-1 Gag are shown in Table 1.
The first 3 inserts (insert 1,2 and 3) aligned to short segments of amino acid residues in HIV-1 gp120. The insert 4 aligned to HIV-1 Gag. The insert 1 (6 amino acid residues) and insert 2 (6 amino acid residues) in the spike glycoprotein of 2019-nCoV are 100% identical to the residues mapped to HIV-1 gp120. The insert 3 (12 amino acid residues) in 2019- nCoV maps to HIV-1 gp120 with gaps [see Table 1]. The insert 4 (8 amino acid residues) maps to HIV-1 Gag with gaps.
Why do the authors think the virus may be man-made? Because when looking at the above insertions which are not present in any of the closest coronavirus families, "it is quite unlikely for a virus to have acquired such unique insertions naturally in a short duration of time." Instead, they can be found in cell identification and membrane binding proteins located in the HIV genome.
Since the S protein of 2019-nCoV shares closest ancestry with SARS GZ02, the sequence coding for spike proteins of these two viruses were compared using MultiAlin software. We found four new insertions in the protein of 2019-nCoV- “GTNGTKR” (IS1), “HKNNKS” (IS2), “GDSSSG” (IS3) and “QTNSPRRA” (IS4) (Figure 2). To our surprise, these sequence insertions were not only absent in S protein of SARS but were also not observed in any other member of the Coronaviridae family (Supplementary figure). This is startling as it is quite unlikely for a virus to have acquired such unique insertions naturally in a short duration of time.
The insertions were observed to be present in all the genomic sequences of 2019-nCoV virus available from the recent clinical isolates. To know the source of these insertions in 2019-nCoV a local alignment was done with BLASTp using these insertions as query with all virus genome. Unexpectedly, all the insertions got aligned with Human immunodeficiency Virus-1 (HIV-1). Further analysis revealed that aligned sequences of HIV-1 with 2019-nCoV were derived from surface glycoprotein gp120 (amino acid sequence positions: 404-409, 462-467, 136-150) and from Gag protein (366-384 amino acid) (Table 1). Gag protein of HIV is involved in host membrane binding, packaging of the virus and for the formation of virus-like particles. Gp120 plays crucial role in recognizing the host cell by binding to the primary receptor CD4.This binding induces structural rearrangements in GP120, creating a high affinity binding site for a chemokine co-receptor like CXCR4 and/or CCR5.
And some visuals, which lead the paper authors to conclude that "this structural change might have also increased the range of host cells that 2019-nCoV can infect":
3D modelling of the protein structure displayed that these insertions are present at the binding site of 2019-nCoV. Due to the presence of gp120 motifs in 2019-nCoV spike glycoprotein at its binding domain, we propose that these motif insertions could have provided an enhanced affinity towards host cell receptors. Further, this structural change might have also increased the range of host cells that 2019-nCoV can infect. To the best of our knowledge, the function of these motifs is still not clear in HIV and need to be explored. The exchange of genetic material among the viruses is well known and such critical exchange highlights the risk and the need to investigate the relations between seemingly unrelated virus families.
A good recap of the findings was provided by Dr. Feigl-Ding, who started his explanatory thread by pointing out that the transmission rate outside China has surpassed the rate inside China.
2) Whoa- the rate of increase ***outside of China*** is steeper than inside of China or Wuhan! Figure 1A. From: @TheLancet “Nowcasting and forecasting the potential domestic and international spread of 2019-nCoV http://bit.ly/2GF6gZP”)
2) Whoa- the rate of increase ***outside of China*** is steeper than inside of China or Wuhan! Figure 1A. From: @TheLancet “Nowcasting and forecasting the potential domestic and international spread of 2019-nCoV http://bit.ly/2GF6gZP”)
3) “An estimated 75815 individuals have been infected in Wuhan” —> this is substantially higher than current reports or ~10k reports by China media. (75k estimate from above Lancet article)
4) ...”On the present trajectory, 2019-nCoV could be about to become a global epidemic in the absence of mitigation...substantial, even draconian measures that limit population mobility should be seriously and immediately considered in affected areas...”
But the 'smoking gun' in this case are pieces of the virus's genetic code that Indian researchers, led by Prashant Pradhan at the Indian Institute of Technology, found may have been 'embedded' from HIV, which belongs to an entirely different family of viruses.
16. UPDATE ON GENOME : a very intriguing new paper investigating the aforementioned mystery middle segment w/ “S” spike protein: likely origin from HIV. “Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag” from https://www.biorxiv.org/content/10.1101/2020.01.30.927871v1 …
17. ...WHOA- the authors said the finding was “Unexpectedly” related to genes from HIV virus. Notably there were 4 gene insertions (see figure in above post #16). And so, which HIV gene proteins were found in the new #coronarvirus? Gag protein and Gp120- key HIV proteins...
18. Notably, in S , authors say for HIVinsertions: “Gag protein of HIV is involved in host membrane binding, packaging of the virus and for the formation of virus-like particles. Gp120 plays crucial role in recognizing the host cell by binding to the primary receptor CD4”
19. Again, these are new express published findings and not peer reviewed yet. Let’s not draw conclusions yet. But evidence suggest that 2 different HIV genes are present in the #coronarvirus S gene region (that didn’t map to any other coronavirus, according to other studies).
20. Further the authors add that “This indicates that these insertions have been preferably acquired by the 2019-nCoV, providing it with additional survival and infectivity advantage. Delving deeper we found that these insertions were similar to HIV-1.”
21. Paper piles on: “these insertions are present at binding site of 2019-nCoV. Due to presence of gp120 motifs in 2019-nCoV spike glycoprotein at its binding domain, we propose that these motif insertions could have provided an enhanced affinity towards host cell receptors.”
22. The authors dunked this final conclusion: “This uncanny similarity of novel inserts in the 2019- nCoV spike protein to HIV-1 gp120 and Gag is unlikely to be fortuitous”. Wow, they sure just went straight there! What a bold paper... I don’t know what to say
9. BOTTOMLINE: 1) Seafood market not the source. 2) This RNA #coronavirus mutates really fast. 3) has unusual middle segment never seen before in any coronavirus. 4) Not from recent mixing. 5) That mystery middle segment encodes protein responsible for entry into host cells.
To be sure, Dr. Feigl-Ding insists that he's not trying to promote any 'conspiracies' about the virus being a bioweapon developed by the Chinese, although it is difficult to find a proper name for what appears to be an artificial, weaponized virus.
10. TO BE CLEAR: I am absolutely not saying it’s bioengineering, nor am I supporting any conspiracy theories with no evidence. I’m simply saying scientists need to do more research + get more data. And finding the origin of the virus is an important research priority. Goodnight
Sure. 2019-nCoV is a +ve strand RNA virus that enters human cell and first encodes its RNA-replicase to make -ve stranded RNA that serves a template to make +ve strand RNA that is then translated for daughter nCoV. Drugs Lopinavir and Remdesivir target its protease and replicase.
Oh my god. Indian scientists have just found HIV (AIDS) virus-like insertions in the 2019-nCov virus that are not found in any other coronavirus. They hint at the possibility that this Chinese virus was designed ["not fortuitous']. Scary if true. https://t.co/h6xPX1gYvjpic.twitter.com/kCpd1I00uE
media. (75k estimate from above Lancet article)
What a bold paper... I don’t know what to say 
GENOME
: a very intriguing new paper investigating the aforementioned mystery middle segment w/ “S” spike protein: likely origin from HIV. “Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag” from biorxiv.org/content/10.110…
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